Processing-induced-transformations (PITs) during direct compression: Impact of tablet composition and compression load on phase transition of caffeine
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چکیده
منابع مشابه
Impact of compression pressure on tablet appearance.
The color of model tablets deepened and tablet gloss increased with increase in compression pressure regardless of colorant type. The possible reasons for these phenomena were examined. These observations could not be explained either by polymorphic transition of the colorant or by condensation of the colorant during compression. Instead, a change in surface roughness was assumed to be the most...
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Fundamentals of Tablet Compression
“Pharmaceutical Processes” discusses scientific and technical principles associated with pharmaceutical unit operations useful to practitioners in compliance and validation. We intend this column to be a useful resource for daily work applications. The primary objective for this column: Useful information. Reader comments, questions, and suggestions are needed to help us fulfill our objectives....
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ژورنال
عنوان ژورنال: International Journal of Pharmaceutics
سال: 2016
ISSN: 0378-5173
DOI: 10.1016/j.ijpharm.2016.01.079